CP violation with a dynamical Higgs

We determine the complete set of independent gauge and gauge-Higgs CP-odd effective operators for the generic case of a dynamical Higgs, up to four derivatives in the chiral expansion. The relation with the linear basis of dimension six CP-odd operators is clarified. Phenomenological applications include bounds inferred from electric dipole moment limits, and from present and future collider data on triple gauge coupling measurements and Higgs signals.Comment: 41 pages, 3 figures; V2: citations added, typos corrected, version published on JHE

Study of thermal protection requirements for a lifting body entry vehicle suitable for near-earth missions Final report

Reentry and abort trajectory analyses, and thermal protection requirements for lifting body entry vehicle

Spatial clustering of mental disorders and associated characteristics of the neighbourhood context in Malmö, Sweden, in 2001

Study objective: Previous research provides preliminary evidence of spatial variations of mental disorders and associations between neighbourhood social context and mental health. This study expands past literature by (1) using spatial techniques, rather than multilevel models, to compare the spatial distributions of two groups of mental disorders (that is, disorders due to psychoactive substance use, and neurotic, stress related, and somatoform disorders); and (2) investigating the independent impact of contextual deprivation and neighbourhood social disorganisation on mental health, while assessing both the magnitude and the spatial scale of these effects. Design: Using different spatial techniques, the study investigated mental disorders due to psychoactive substance use, and neurotic disorders. Participants: All 89 285 persons aged 40–69 years residing in Malmö, Sweden, in 2001, geolocated to their place of residence. Main results: The spatial scan statistic identified a large cluster of increased prevalence in a similar location for the two mental disorders in the northern part of Malmö. However, hierarchical geostatistical models showed that the two groups of disorders exhibited a different spatial distribution, in terms of both magnitude and spatial scale. Mental disorders due to substance consumption showed larger neighbourhood variations, and varied in space on a larger scale, than neurotic disorders. After adjustment for individual factors, the risk of substance related disorders increased with neighbourhood deprivation and neighbourhood social disorganisation. The risk of neurotic disorders only increased with contextual deprivation. Measuring contextual factors across continuous space, it was found that these associations operated on a local scale. Conclusions: Taking space into account in the analyses permitted deeper insight into the contextual determinants of mental disorders

STRENGTHENING COOPERATION WITH THIRD COUNTRIES IN THE FIELD OF HIGHER EDUCATION. 14388/01 (Presse 437-G), 29 November 2001

BACKGROUND: In many European countries, medicines promotion is governed by voluntary codes of practice administered by the pharmaceutical industry under its own system of self-regulation. Involvement of industry organizations in policing promotion has been proposed to deter illicit conduct, but few detailed studies on self-regulation have been carried out to date. The objective of this study was to examine the evidence for promotion and self-regulation in the UK and Sweden, two countries frequently cited as examples of effective self-regulation. METHODS AND FINDINGS: We performed a qualitative content analysis of documents outlining the constitutions and procedures of these two systems. We also gathered data from self-regulatory bodies on complaints, complainants, and rulings for the period 2004-2012. The qualitative analysis revealed similarities and differences between the countries. For example, self-regulatory bodies in both countries are required to actively monitor promotional items and impose sanctions on violating companies, but the range of sanctions is greater in the UK where companies may, for instance, be audited or publicly reprimanded. In total, Swedish and UK bodies ruled that 536 and 597 cases, respectively, were in breach, equating to an average of more than one case/week for each country. In Sweden, 430 (47%) complaints resulted from active monitoring, compared with only two complaints (0.2%) in the UK. In both countries, a majority of violations concerned misleading promotion. Charges incurred on companies averaged €447,000 and €765,000 per year in Sweden and the UK, respectively, equivalent to about 0.014% and 0.0051% of annual sales revenues, respectively. One hundred cases in the UK (17% of total cases in breach) and 101 (19%) in Sweden were highlighted as particularly serious. A total of 46 companies were ruled in breach of code for a serious offence at least once in the two countries combined (n = 36 in the UK; n = 27 in Sweden); seven companies were in serious violation more than ten times each. A qualitative content analysis of serious violations pertaining to diabetes drugs (UK, n = 15; Sweden, n = 6; 10% of serious violations) and urologics (UK, n = 6; Sweden, n = 13; 9%) revealed various types of violations: misleading claims (n = 23; 58%); failure to comply with undertakings (n = 9; 23%); pre-licensing (n = 7; 18%) or off-label promotion (n = 2; 5%); and promotion of prescription drugs to the public (n = 6; 15%). Violations that go undetected or unpunished by self-regulatory bodies are the main limitation of this study, since they are likely to lead to an underestimate of industry misconduct. CONCLUSIONS: The prevalence and severity of breaches testifies to a discrepancy between the ethical standard codified in industry Codes of Conduct and the actual conduct of the industry. We discuss regulatory reforms that may improve the quality of medicines information, such as pre-vetting and intensified active monitoring of promotion, along with larger fines, and giving greater publicity to rulings. But despite the importance of improving regulatory arrangements in an attempt to ensure unbiased medicines information, such efforts alone are insufficient because simply improving oversight and increasing penalties fail to address additional layers of industry bias

Higgs ultraviolet softening

We analyze the leading effective operators which induce a quartic momentum dependence in the Higgs propagator, for a linear and for a non-linear realization of electroweak symmetry breaking. Their specific study is relevant for the understanding of the ultraviolet sensitivity to new physics. Two methods of analysis are applied, trading the Lagrangian coupling by: i) a "ghost" scalar, after the Lee-Wick procedure; ii) other effective operators via the equations of motion. The two paths are shown to lead to the same effective Lagrangian at first order in the operator coefficients. It follows a modification of the Higgs potential and of the fermionic couplings in the linear realization, while in the non-linear one anomalous quartic gauge couplings, Higgs-gauge couplings and gauge-fermion interactions are induced in addition. Finally, all LHC Higgs and other data presently available are used to constrain the operator coefficients; the future impact of $pp\to\text{4 leptons}$ data via off-shell Higgs exchange and of vector boson fusion data is considered as well. For completeness, a summary of pure-gauge and gauge-Higgs signals exclusive to non-linear dynamics at leading-order is included.Comment: 31 pages, 3 figures, 7 table

Disentangling a dynamical Higgs

The pattern of deviations from Standard Model predictions and couplings is different for theories of new physics based on a non-linear realization of the $SU(2)_L\times U(1)_Y$ gauge symmetry breaking and those assuming a linear realization. We clarify this issue in a model-independent way via its effective Lagrangian formulation in the presence of a light Higgs particle, up to first order in the expansions: dimension-six operators for the linear expansion and four derivatives for the non-linear one. Complete sets of pure gauge and gauge-Higgs operators are considered, implementing the renormalization procedure and deriving the Feynman rules for the non-linear expansion. We establish the theoretical relation and the differences in physics impact between the two expansions. Promising discriminating signals include the decorrelation in the non-linear case of signals correlated in the linear one: some pure gauge versus gauge-Higgs couplings and also between couplings with the same number of Higgs legs. Furthermore, anomalous signals expected at first order in the non-linear realization may appear only at higher orders of the linear one, and vice versa. We analyze in detail the impact of both type of discriminating signals on LHC physics.Comment: Version published in JHE

A New bound on CP Violation in the τ\tau Lepton Yukawa Coupling and electroweak baryogenesis

The origin of the matter-antimatter asymmetry in the Universe is a fundamental question of physics. Electroweak baryogenesis is a compelling scenario for explaining it but it requires beyond the Standard Model sources of the CP symmetry violation. The simplest possibility is CP violation in the third generation fermion Higgs couplings, widely investigated theoretically and searched for experimentally. It has been found that the experimental bounds on the CP violation in the quark Yukawa couplings exclude their significant role in the electroweak baryogenesis, but it can be still played by the $\tau$ lepton Yukawa coupling. It is shown in this paper that, within the context of the Standard Model Effective Field Theory and assuming an underlying flavour symmetry of the Wilson coefficients, the electron dipole moment bound on the $\tau$ lepton Yukawa coupling is two orders of magnitude stronger than previously reported. This sheds strong doubts on its role in the electroweak baryogenesis, further stimulates the interest in its experimental verification and makes electroweak baryogenesis even more difficult to explain.Comment: V2: references added; minor changes on the text; results unchanged; version accepted for publication on JHE